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Published data show that deficiency typically emerges around 6 months post-bariatric surgery, with peak incidence at 12 months or longer (1)

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Elevated expression of IGF-IR in BCR/ABL + cells may promote the development and self-renewal of chronic myeloid leukemia, while downregulation of IGF-IR in BCR/ABL + cells leads to acute lymphoblastic leukemia (ALL) [14]

It can be used to study how the metabolism of acetaminophen depends on the expression level of liver enzymes